Our Publications

Inversion and deletion of 16q22 defined by array CGH, FISH, and RT-PCR in a patient with AML.

Dawson AJ, Bal S, McTavish B, Tomiuk M, Schroedter I, Ahsanuddin AN, Seftel MD, Vallente R, Mai S, Cotter PD, Hovanes K, Gorre M, Gunn SR. Inversion and deletion of 16q22 defined by array CGH, FISH, and RT-PCR in a patient with AML. Cancer Genet. 2011 Jun;204(6):344-7. http://www.ncbi.nlm.nih.gov/pubmed/21763633

Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity.

Gunn SR, Yeh IT, Lytvak I, Tirtorahardjo B, Dzidic N, Zadeh S, Kim J, McCaskill C, Lim L, Gorre M, Mohammed M. Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity. BMC Cancer 2010, 10:396 (28 July 2010)http://www.ncbi.nlm.nih.gov/pubmed/20667129

Array-based karyotyping for prognostic markers in chronic lymphocytic leukemia

Gunn SR. The vanguard has arrived in the clinical laboratory: array-based karyotyping for prognostic markers in chronic lymphocytic leukemia. J Mol Diagn. 2010 Mar;12(2):144-6. http://www.ncbi.nlm.nih.gov/pubmed/20075205

Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event.

Yeh IT, Martin MA, Robetorye RS, Bolla AR, McCaskill C, Shah RK, Gorre ME, Mohammed MS, Gunn SR. Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event. Mod Pathol. 2009 Sep;22(9):1169-75. http://www.ncbi.nlm.nih.gov/pubmed/19448591

Array CGH analysis of chronic lymphocytic leukemia reveals frequent cryptic monoallelic and biallelic deletions of chromosome 22q11 that include the PRAME gene.

Gunn SR, Bolla AR, Barron LL, Gorre ME, Mohammed MS, Bahler DW, Mellink CH, van Oers MH, Keating MJ, Ferrajoli A, Coombes KR, Abruzzo LV, Robetorye RS. Array CGH analysis of chronic lymphocytic leukemia reveals frequent cryptic monoallelic and biallelic deletions of chromosome 22q11 that include the PRAME gene. Leuk Res. 2009 Sep;33(9):1276-81.http://www.ncbi.nlm.nih.gov/pubmed/19027161

Molecular characterization of a patient with central nervous system dysmyelination and cryptic unbalanced translocation between chromosomes 4q and 18q

Gunn SR, Mohammed M, Reveles XT, Viskochil DH, Palumbos JC, Johnson-Pais TL, Hale DE, Lancaster JL, Hardies LJ, Boespflug-Tanguy O, Cody JD, Leach RJ. Molecular characterization of a patient with central nervous system dysmyelination and cryptic unbalanced translocation between chromosomes 4q and 18q. Am J Med Genet A. 2003 Jul 1;120A(1):127-35. http://www.ncbi.nlm.nih.gov/pubmed/12794705

Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia.

Gunn SR, Mohammed MS, Gorre ME, Cotter PD, Kim J, Bahler DW, Preobrazhensky SN, Higgins RA, Bolla AR, Ismail SH, de Jong D, Eldering E, van Oers MH, Mellink CH, Keating MJ, Schlette EJ, Abruzzo LV, Robetorye RS. Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia. J Mol Diagn. 2008 Sep;10(5):442-51.http://www.ncbi.nlm.nih.gov/pubmed/18687794

Use of DNA sequencing analysis to confirm fungemia due to Trichosporon dermatis in a pediatric patient. J Clin Microbiol.

Gunn SR, Reveles XT, Hamlington JD, Sadkowski LC, Johnson-Pais TL, Jorgensen JH. Use of DNA sequencing analysis to confirm fungemia due to Trichosporon dermatis in a pediatric patient. J Clin Microbiol. 2006 Mar;44(3):1175-7.http://www.ncbi.nlm.nih.gov/pubmed/16517924

Detection of recurrent copy number loss at Yp11.2 involving TSPY gene cluster in prostate cancer using array-based comparative genomic hybridization.

Vijayakumar S, Hall DC, Reveles XT, Troyer DA, Thompson IM, Garcia D, Xiang R, Leach RJ, Johnson-Pais TL, Naylor SL. Detection of recurrent copy number loss at Yp11.2 involving TSPY gene cluster in prostate cancer using array-based comparative genomic hybridization. Cancer Res. 2006 Apr 15;66(8):4055-64.http://www.ncbi.nlm.nih.gov/pubmed/16618725

Chromosome 18 suppresses prostate cancer metastases.

Padalecki SS, Weldon KS, Reveles XT, Buller CL, Grubbs B, Cui Y, Yin JJ, Hall DC, Hummer BT, Weissman BE, Dallas M, Guise TA, Leach RJ, Johnson-Pais TL. Chromosome 18 suppresses prostate cancer metastases. Urol Oncol. 2003 Sep-Oct;21(5):366-73. http://www.ncbi.nlm.nih.gov/pubmed/14670546

Comparative genomic hybridization arrays in clinical pathology: progress and challenges.

Gunn SR, Robetorye RS, Mohammed MS. Comparative genomic hybridization arrays in clinical pathology: progress and challenges. Mol Diagn Ther. 2007;11(2):73-7.http://www.ncbi.nlm.nih.gov/pubmed/17397242

Clinical application of array-based comparative genomic hybridization for the identification of prognostically important genetic alterations in chronic lymphocytic leukemia.

Higgins RA, Gunn SR, Robetorye RS. Clinical application of array-based comparative genomic hybridization for the identification of prognostically important genetic alterations in chronic lymphocytic leukemia. Mol Diagn Ther. 2008;12(5):271-80.http://www.ncbi.nlm.nih.gov/pubmed/18803425

Atypical 11q deletions identified by array CGH may be missed by FISH panels for prognostic markers in chronic lymphocytic leukemia.

Gunn SR, Hibbard MK, Ismail SH, Lowery-Nordberg M, Mellink CH, Bahler DW, Abruzzo LV, Enriquez EL, Gorre ME, Mohammed MS, Robetorye RS. Atypical 11q deletions identified by array CGH may be missed by FISH panels for prognostic markers in chronic lymphocytic leukemia. Leukemia 2009 May;23(5):1011-7.http://www.ncbi.nlm.nih.gov/pubmed/19158838

PHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumors.

Deshpande AM, Akunowicz JD, Reveles XT, Patel BB, Saria EA, Gorlick RG, Naylor SL, Leach RJ, Hansen MF. PHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumors. Oncogene. 2007 Mar 15;26(12):1714-22. http://www.ncbi.nlm.nih.gov/pubmed/17001316

Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer.

Schneider BG, Rha SY, Chung HC, Bravo JC, Mera R, Torres JC, Plaisance KT Jr, Schlegel R, McBride CM, Reveles XT, Leach RJ. Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer. Mol Pathol. 2003 Jun;56(3):141-9. http://www.ncbi.nlm.nih.gov/pubmed/12782760

Association of chromosome 8q variants with prostate cancer risk in Caucasian and Hispanic men.

Beuten J, Gelfond JA, Martinez-Fierro ML, Weldon KS, Crandall AC,Rojas-Martinez A, Thompson IM, Leach RJ. Association of chromosome 8q variants with prostate cancer risk in Caucasian and Hispanic men. Carcinogenesis. 2009 Aug;30(8):1372-9. Epub 2009 Jun 15. http://www.ncbi.nlm.nih.gov/pubmed?term=Beuten%20J%20and%208q

Single and multigenic analysis of the association between variants in 12 steroid hormone metabolism genes and risk of prostate cancer.

Beuten J, Gelfond JA, Franke JL, Weldon KS, Crandall AC, Johnson-Pais TL, Thompson IM, Leach RJ. Single and multigenic analysis of the association between variants in 12 steroid hormone metabolism genes and risk of prostate cancer.  Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1869-80.http://www.ncbi.nlm.nih.gov/pubmed/19505920